Atriopeptin (rat) ELISA Kit

Atriopeptin is a 28 amino acid peptide synthesised primarily in cardiac atria. This peptide hormone acts in an opposing manner to angiotensin in regulating renal, hemodynamic and endocrine function. Elevated plasma levels may be produced in experimental models by volume expansion, high salt diets, and vasoconstrictors. Increased plasma concentrations have also been reported in various pathological conditions such as renal disease, congestive heart failure, and paroxysmal atrial tachycardia. Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence). Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.