MIP-1β (pig) ELISA Kit

Macrophage inflammation protein-1β (MIP-1β), also known as CCL4, is a C-C Chemokine produced by macrophages after stimulation by bacterial endotoxins. This chemokine is crucial for immune responses towards infection and inflammation. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. When produced by CD8+ T cells, MIP-1β is also a major HIV-suppressive factor. Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence). Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.