CXCL10 (pig) ELISA Kit

CXCL10 is also known as Interferon gamma-induced protein 10 (IP-10) or small-inducible cytokine B10 with a molecular weight close to 10 kDa. CXCL10 is expressed by several cellular types like monocytes, endothelial cells and fibroblasts stimulated by the interferon-γ (INF-γ). The receptor of this chemokine is CXCR3 that is shared with CXCL9 and CXCL11. CXCL-10 plays an important role in the recruitment of the immune cells to sites of inflammation. It is included in physiological process like bone marrow colony formation and angiogenesis but also in some disorders like Th1-type human inflammatory diseases, or cancer. Enzyme ImmunoAssay (EIA) is a technique to detect and quantify antigens (proteins, hormones�) or antibodies in samples. It relies on the ability of an antibody to bind a specific antigen. Either the antibody or the antigen is labelled with an enzyme whose substrate is a chromogen or a fluorogen converted in a measurable product (color or fluorescence). Enzyme-linked Immunosorbent Assay (ELISA) is a type of EIA using a solid phase (ex: microtiter plate) coated with an antigen immobilizing the molecule to detect. Over the time, scientists have extended the term ELISA to EIAs using an antibody coating the solid phase. That explains why our EIA kits using coated antibodies are also called ELISA kits.