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Bertin Bioreagent
anti-2-3-dinor Thromboxane B2, pAb
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CHF 579.00
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BRT-C03044-T500500 dtnCHF 579.00
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| Product Details | |
|---|---|
| Synonyms | 2-3 Dinor TXB2 Polyclonal Antibody |
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | TXB2-BSA. |
| Application | RIA |
| Specificity | % CROSS REACTIVITY for B/Bo = 50 % (DH = 13,14-dihydro ; K = 15-keto), A1 < 0,04, B1 < 0,04, D1 0,09, E1 < 0,04, DH E1 < 0,04, K E1 < 0,04, DHK E1 < 0,04, F1 < 0,04, DH F1 < 0,04, K F1 < 0,04, DHK F1 < 0,04, 19-OH E1 < 0,04, 6-keto E1 < 0,04, 6-keto F1 < 0,04, 6,15-dik |
| Formulation | Liquid. This vial contains 500 determinations of antibody in 1/2 glyceroled liquid for a total volume of 50 µL. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. 2,3-dinor TXB2 is an abundant urinary metabolite of TXB2 and can be used as a marker for in vivo TXA2 synthesis. Urinary levels of TXB2 reflect intrarenal TXA2 synthesis, while its metabolites, 11-dehydro TXB2 and 2,3-dinor TXB2, reflect systemic TXA2 secretion.