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Bertin Bioreagent
anti-Prostaglandin E1, pAb
As low as
579
CHF
CHF 579.00
In stock
Only %1 left
BRT-C03046-T500500 dtnCHF 579.00
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| Product Details | |
|---|---|
| Synonyms | PGE1; Alprostadil |
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Sheep |
| Immunogen/Antigen | PGE1-BSA. |
| Application | RIA |
| Specificity | % CROSS REACTIVITY for B/Bo = 50 %, A1 0.1, B1 <0.1, D1 0.1, E1 100, K E1 0.2, DHK E1 0.2, F1 0.2, A2 <0.1, B2 <0.1, D2 <0.1, E2 15, K E2 <0.1, DHK E2 <0.1, F2 0.1, |
| Formulation | Liquid. This vial contains 500 determinations of antibody in 1/2 glyceroled liquid for a total volume of 25 µL. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Prostaglandin E1 (PGE1) is a vasoactive prostaglandin and an active metabolite of dihomo-gamma-linolenic acid (DGLA). It is formed from DGLA by COX-1 and COX-2. PGE1 is an agonist of the PGE2 receptor subtypes EP1, EP2, EP3, and EP4, and the IP receptor. PGE1 is a potent signaling molecule with diverse clinical applications in cardiovascular, reproductive, and gastrointestinal health. It has vasodilation, anti-inflammatory, platelet inhibition, gastroprotective and smooth muscle relaxant activities. Formulations containing PGE1 have been used in the treatment of erectile dysfunction and to maintain patency of the ductus arteriosus in neonates with congenital heart defects who depend on a patent ductus arteriosus for survival.