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Bertin Bioreagent
anti-13,14-dihydro-15-keto Prostaglandin E2, pAb
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CHF 579.00
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BRT-C03049-T500500 dtnCHF 579.00
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| Product Details | |
|---|---|
| Synonyms | 13,14-dihydro-15-keto PGE2; 13,14-dihydro-oxo-PGE2; PGEM |
| Product Type | Polyclonal Antibody |
| Properties | |
| Source/Host | Rabbit |
| Immunogen/Antigen | 13,14-dihydro-15-keto PGE1-BSA. |
| Application | RIA |
| Specificity | % CROSS REACTIVITY for B/Bo = 50 %, DH E1 3,4, K E1 2,5, DHK E1 68, K F1 0,18, A2 0,15, B2 0,05, E2 < 0,01, DH E2 2,3, K E2 1,8, DHK E2 100, F2 0,17, K F2 0,7, DHKF2 22, |
| Formulation | Liquid. This vial contains 500 determinations of antibody for a total volume of 100 µL. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
13,14-dihydro-15-keto Prostaglandin E2 is a metabolite of PGE2 and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG ?13 reductase. Does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells. Levels of 13,14-dihydro-15-keto PGE2 are increased in the plasma of women in the third trimester of pregnancy and in women during and immediately after labor and delivery. Levels of 13,14-dihydro-15-keto PGE2 levels are decreased in tumor tissue compared to adjacent non-cancerous tissue isolated from patients with non-small cell lung cancer (NSCLC).