anti-Methionine Enkephalin, pAb

Methionine Enkephalin (Met-Enkephalin) is an endogenous neuropeptide involved in nociception and an agonist of δ- and μ-opioid receptors. Met-Enkephalin is a cleavage product of proenkephalin, which is found primarily in the adrenal medulla and the CNS. It is one of the two main forms of enkephalins, the other being leucine enkephalin. Like other opioid peptides, methionine enkephalin plays a role in reducing pain perception. It acts on the opioid receptors (specifically delta opioid receptors), which are involved in modulating pain signals in the nervous system. Methionine enkephalin is involved in regulating mood and emotional responses, contributing to feelings of well-being. It may also have roles in the regulation of blood pressure, appetite, and immune responses. Levels of methionineenkephalin are increased at the site of inflammation in a complete Freund�s adjuvant mouse model of chronic inflammatory pain.