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Bertin Bioreagent
anti-Estrogen receptor α (B region), mAb (B10)
As low as
664
CHF
CHF 664.00
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BRT-G01008-R100100 µlCHF 664.00
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| Product Details | |
|---|---|
| Synonyms | ERalpha; Estradiol receptor; Nuclear Receptor Subfamily 3 Group A Member 1 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | B10 |
| Isotype | Mouse IgG2aκ |
| Source/Host | Mouse |
| Application |
Immunohistochemistry, Immunocytochemistry, ELISA, Western Blot IHC: frozen section and microwave oven treated paraffin sections (Suggested dilution 1/1000-1/2000) ICC (Suggested dilution 1/1000-1/2000) Elisa (Suggested dilution 1/1000-1/2000) |
| Specificity | Recognizes human ER (B region) in the region of aa 151-165. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Estrogen receptors (ERs) are nuclear hormone receptors that mediate the effects of 17β-Estradiol (E2) and estrogen (E1), key sex hormones in both females and males. These receptors are transcription factors, meaning they regulate gene expression when activated. Estrogen receptors (ERα & ERβ) play a major role in growth, reproduction, metabolism, and disease processes. They regulate gene expression and influence breast cancer, bone health, heart function, and brain activity. ERα is pro-growth and linked to breast cancer, while ERβ may have protective effects.