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Bertin Bioreagent
anti-RNA Polymerase I, mAb (2D3)
As low as
777
CHF
CHF 777.00
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BRT-G01033-R100100 µlCHF 777.00
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Product Details | |
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Synonyms | Pol I; DNA-directed RNA Polymerase I; Ribosomal RNA Polymerase; RNA Pol I |
Product Type | Monoclonal Antibody |
Properties | |
Clone | 2D3 |
Isotype | Mouse IgG2aκ |
Source/Host | Mouse |
Immunogen/Antigen | Synthetic peptide. |
Application | ELISA, Western Blot, Immunofluorescence. Recommended dilution: 1/500-1/5000 |
Specificity | Recognizes human Polymerase I. |
Formulation | Liquid. Does not contain any preservative. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
Declaration | Manufactured by Bertin Bioreagent |
Shipping and Handling | |
Shipping | BLUE ICE |
Long Term Storage | -20°C |
Handling Advice | Avoid freeze/thaw cycles. |
Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
Documents | |
Product Specification Sheet | |
Datasheet |
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Description
RNA Polymerase I (Pol I) is an enzyme responsible for transcribing ribosomal RNA (rRNA) in eukaryotic cells. It plays a crucial role in ribosome biogenesis, which is essential for protein synthesis. Hyperactivation of Pol I is observed in many cancers and disruptions in rRNA synthesis have been linked to disorders like Parkinson�s and Alzheimer�s.