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Bertin Bioreagent
anti-Snail, mAb (5H6)
As low as
664
CHF
CHF 664.00
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Only %1 left
BRT-G01040-R100100 µlCHF 664.00
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| Product Details | |
|---|---|
| Synonyms | Zinc finger protein SNAI1; SNAIL |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 5H6 |
| Isotype | Mouse IgG1κ |
| Source/Host | Mouse |
| Immunogen/Antigen | Recombinant drosophila snail protein. |
| Application | ELISA, Western Blot, Immunocytochemistry. Recommended dilutions: 1/500-1/5000 |
| Specificity | Recognizes Drosophila snail protein. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Zinc finger protein SNAI1 (SNAIL) is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAIL acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAIL and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumors.