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Bertin Bioreagent
anti-SUMO1 (Small ubiquitin-related modifier 1), mAb (1C6)
As low as
CHF 778.00
In stock
Only %1 left
BRT-G01063-R100100 µlCHF 778.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | Small Ubiquitin-related Modifier 1; GAP-modifying Protein 1; SMT3C, SMT3H3, UBL1; Sentrin; Ubiquitin-homology Domain Protein PIC1 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 1C6 |
| Isotype | Mouse IgG2bκ |
| Source/Host | Mouse |
| Immunogen/Antigen | Synthetic peptide coupled to ovalbumin. |
| Application | ELISA, Western Blot. Recommended dilutions: 1/500-1/5000. |
| Specificity | Recognizes human and mouse SUMO1. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
SUMO1 is a ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction.