Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Bertin Bioreagent
anti-TAF11, mAb (2B4)
As low as
664
CHF
CHF 664.00
In stock
Only %1 left
BRT-G01077-R100100 µlCHF 664.00
NEW
| Product Details | |
|---|---|
| Synonyms | Transcription Initiation Factor TFIID Subunit 11; TATA-Box Binding Protein-Associated Factor 11; TAFII28 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 2B4 |
| Isotype | Mouse IgG1κ |
| Source/Host | Mouse |
| Immunogen/Antigen | Recombinant human TAF11 protein. |
| Application | ELISA, Western Blot, Immunoprecipitation, Immunofluorescence. Recommended dilutions: 1/500-1/5000. |
| Specificity | Recognizes human and mouse TAF11. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
TAF11 is a core component of the TFIID complex, a critical regulator of RNA polymerase II-dependent transcription initiation. It functions as a transcription cofactor in the assembly and stabilization of the TFIID complex. TAF11 is a TATA-binding protein-associated factor (TAF) within TFIID, which is essential for recognizing core promoter elements and recruiting RNA polymerase II. TAF11 is important for cell differentiation and embryonic development, as transcription regulation is key in tissue-specific gene expression. Since TAF11 regulates transcription, its dysfunction may contribute to cancer and other diseases associated with altered gene expression.