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Bertin Bioreagent
anti-TAF12 (formerly TAFII20), mAb (2A1)
As low as
664
CHF
CHF 664.00
In stock
Only %1 left
BRT-G01078-R100100 µlCHF 664.00
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| Product Details | |
|---|---|
| Synonyms | Transcription Initiation Factor TFIID Subunit 12; TATA-Box Binding Protein-Associated Factor 12; TAFII20/TAFII15 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 2A1 |
| Isotype | Mouse IgG1κ |
| Source/Host | Mouse |
| Immunogen/Antigen | Recombinant human TAF12 protein. |
| Application | ELISA, Western Blot, Immunoprecipitation, Immunofluorescence. Recommended dilutions: 1/500-1/5000. |
| Specificity | Recognizes human and mouse TAF12. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
TAF12 is a transcription cofactor and a core subunit of the TFIID complex, which is essential for RNA polymerase II-dependent transcription initiation. It plays a critical role in gene expression regulation and chromatin remodeling. TAF12 interacts with TAF4, TAF5, and TAF6, helping to assemble and stabilize the TFIID complex. TAF12 is also found in the SAGA (Spt-Ada-Gcn5 Acetyltransferase) complex, which regulates gene expression through histone acetylation. TAF12 dysfunction can lead to abnormal gene expression and is linked to tumorigenesis.