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Bertin Bioreagent
anti-TFIIH p44, mAb (1H5)
As low as
CHF 664.00
In stock
Only %1 left
BRT-G01096-R100100 µlCHF 664.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | TFIIH Basal Transcription Factor p44; General Transcription Factor IIH Subunit 2; GTF2H2; BTF2 p44 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 1H5 |
| Isotype | Mouse IgG1κ |
| Source/Host | Mouse |
| Immunogen/Antigen | Synthetic peptide. |
| Application | ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry. Recommended dilutions: 1/500-1/5000. |
| Specificity | Recognizes human TFIIHp44. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
TFIIH is a multi-subunit protein complex involved in transcription and DNA repair. TFIIH p44 as a scaffold protein helps to stabilize the TFIIH complex. It stimulates the ATPase and helicase activity of XPB (ERCC3), a DNA helicase essential for unwinding DNA during transcription and repair and plays a role in RNA polymerase II transcription and nucleotide excision repair (NER) by facilitating the recruitment of other factors to damaged DNA.