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Bertin Bioreagent
anti-TFIIH p52 (TFIIH basal transcription factor p52), mAb (1D11)
As low as
CHF 664.00
In stock
Only %1 left
BRT-G01097-R100100 µlCHF 664.00
Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | TFIIH Basal Transcription Factor p52; General Transcription Factor IIH Subunit 4; GTF2H4; BTF2 p52 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 1D11 |
| Isotype | Mouse IgG1κ |
| Source/Host | Mouse |
| Immunogen/Antigen | Synthetic peptide. |
| Application | ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry. Recommended dilutions: 1/500-1/5000. |
| Specificity | Recognizes human TFIIHp52. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
TFIIH is a multi-subunit protein complex involved in transcription and DNA repair. TFIIH p52 plays a critical role in stabilizing TFIIH and regulating its helicase activity. It interacts with XPB (ERCC3), a helicase essential for DNA unwinding. It is required for RNA polymerase II transcription initiation and nucleotide excision repair (NER) and regulates the activity of other TFIIH subunits, including CDK7, which is involved in phosphorylation of RNA polymerase II.