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Bertin Bioreagent
anti-TFIIH p62 (TFIIH basal transcription factor p62), mAb (3C9)
As low as
664
CHF
CHF 664.00
In stock
Only %1 left
BRT-G01098-R100100 µlCHF 664.00
| Product Details | |
|---|---|
| Synonyms | TFIIH Basal Transcription Factor p62; General Transcription Factor IIH Subunit 1; GTF2H1; BTF2 p62 |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | 3C9 |
| Isotype | Mouse IgG1κ |
| Source/Host | Mouse |
| Immunogen/Antigen | Recombinant human TFIIHp62. |
| Application | ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry. Recommended dilutions: 1/500-1/5000. |
| Specificity | Recognizes human TFIIHp62. |
| Formulation | Liquid. Does not contain any preservative. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Bertin Bioreagent |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
TFIIH is a multi-subunit protein complex involved in transcription and DNA repair. TFIIH p62 acts as a scaffold protein, helping to organize and stabilize the TFIIH complex. It plays a role in RNA polymerase II transcription initiation by mediating interactions with other transcription factors. TFIIH p62 is essential for nucleotide excision repair (NER) by facilitating the recruitment and proper assembly of TFIIH at sites of DNA damage and it interacts with XPB (ERCC3) and XPD (ERCC2), helicases necessary for DNA unwinding in both transcription and repair.