Polyketomycin

CHF 175.00
In stock
BVT-0033-M0011 mgCHF 175.00
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Product Details
Synonyms Antibiotic K99-5147
Product Type Chemical
Properties
Formula

C44H48O18

MW 864.8
CAS 200625-47-4
Source/Host Chemicals Isolated from Streptomyces sp.
Purity Chemicals ≥98% (HPLC)
Appearance Orange to dark brown solid.
Solubility Soluble in DMSO, methanol or acetone.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key OWRCRVABZYJUES-FLJLGRLJSA-N
Smiles [H][C@@]1(CC[C@H](O[C@@]2([H])C[C@@](C)(O)[C@H](OC(=O)C3=C(C)C=CC(C)=C3O)[C@H](C)O2)[C@@H](C)O1)O[C@@H]1C(=O)\C(=C(\C)O)C(=O)[C@@]2(O)C(=O)C3=C(C[C@@]12O)C(C)=C1C(=O)C(OC)=CC(=O)C1=C3O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Tetracyclic quinone glycoside.
  • Antibacterial and antimalarial.
  • Antitumor compound.
Product References
  1. Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities: I. Momose, et al.; J. Antibiot. 51, 21 (1998)
  2. Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. II. Structure determination: I. Momose, et al.; J. Antibiot. 51, 26 (1998)
  3. Biosynthesis of polyketomycin produced by Streptomyces diastatochromogenes Tü 6028: T. Paululat, et al.; J. Antibiot. 52, 96 (1999)
  4. In vitro antimalarial activities of the microbial metabolites: K. Otoguro, et al.; J. Antibiot. 56, 322 (2003)
  5. Synthesis of the polyketomycin disaccharide: D.S. Micalizzi, et al.; Tetrahedron: Asymmetry 14, 3183 (2003)
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