5-Hydroxymethylcytosine

CHF 155.00
In stock
BVT-0229-M01010 mgCHF 155.00
 
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Product Details
Synonyms 5hmC; Demethylbacimethrin
Product Type Chemical
Properties
Formula C5H7N3O2
MW 141.1
CAS 1123-95-1
Source/Host Chemicals Synthetic.
Purity Chemicals ≥98% (NMR)
Appearance Off-white powder.
Solubility Soluble in water, DMSO or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key RYVNIFSIEDRLSJ-UHFFFAOYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Modified base of mammalian DNA.
  • Involved in regulation of stem cell processes, cellular development, neurodegeneration and carcinogenesis.
  • Important epigenetic marker.
  • Related to bacimethrin (Prod. No. BVT-0226).
Product References
  1. 5-Hydroxymethylcytosine, the sixth base of the genome: M. Münzel, et al.; Angew. Chem. Int. Ed. 50, 6420 (2011) (Review)
  2. 5-Hydroxymethylcytosine-mediated DNA demethylation in stem cells and development: W. Sun; Stem Cells 23, 923 (2014) (Review)
  3. 5-Hydroxymethylcytosine: an epigenetic mark frequently deregulated in cancer: L. Kroetze, et al.; Biochim. Biophys. Acta 144, 1855 (2015) (Review)
  4. 5-Hydroxymethylcytosine: a new player in brain disorders?: Y. Cheng, et al.; Exp. Neurol. 268, 3 (2015) (Review)
  5. 5-Hydroxymethylcytosine: in cancer: significance in diagnosis and therapy: A. Vasanthakumar & L. A. Godley; Cancer Genet. 208, 167 (2015) (Review)
  6. New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine: E. Moen, et al.; Immunol. Rev. 236, 36 (2015) (Review)
  7. Role of 5-hydroxymethylcytosine in neurodegeneration: S. I. Sherwani & H. A. Khan; Gene 570, 17 (2015) (Review)
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