CHF 155.00
In stock
BVT-0289-C500500 µgCHF 155.00
BVT-0289-M0011 mgCHF 265.00
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Product Details
Synonyms Helmidiol; (-)-Pyrenophorol; (3E,5S,8R,11E,13S,16R)-5,13-Dihydroxy-8,16-dimethyl-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione
Product Type Chemical


MW 312.4
CAS 155326-45-7 and 22248-41-5
Source/Host Chemicals Isolated from Phoma sp.
Purity Chemicals ≥98% (HPLC)
Appearance White to off-white solid.
Solubility Soluble in DMSO (5 mg/ml), methanol (5 mg/ml) or dichloromethane.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
Smiles C[C@@H]1CC[C@H](O)\C=C\C(=O)O[C@H](C)CC[C@H](O)\C=C\C(=O)O1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Phytotoxic, antifungal and anthelmintic.
  • Prolyl endopeptidase inhibitor.
Product References
  1. Secondary Metabolites by Chemical Screening. 30.1 Helmidiol, a New Macrodiolide from Alternaria alternata.: R. Kind, et al.; J. Nat. Prod. 59, 539 (1996)
  2. Albocycline- and carbomycin-type macrolides, inhibitors of human prolylendopeptidases.: C. Christner, et al.; J. Antibiot. 51, 368 (1998)
  3. Bioactivity of the fungal metabolite (8R,16R)-(-)-pyrenophorin on graminaceous plants.: M.A. Kastanias, et al.; J. Agric. Food Chem. 53, 5943 (2005)
  4. Diversity of antimicrobial pyrenophorol derivatives from an endophytic fungus, Phoma sp.: W. Zang, et al.; Eur. J. Org. Chem. 2008, 4320 (2008)
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