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BioViotica
Antibiotic L-696,474
155
CHF
CHF 155.00
In stock
BVT-0331-C500500 µgCHF 155.00
| Product Details | |
|---|---|
| Synonyms | 18-Dehydroxycytochalasin H |
| Product Type | Chemical |
| Properties | |
| Formula |
C30H39NO4 |
| MW | 477.6 |
| CAS | 141994-72-1 |
| Source/Host Chemicals | Isolated from Hypoxylon fragiforme. |
| Purity Chemicals | ≥98% (HPLC; NMR) |
| Appearance | White powder. |
| Solubility | Soluble in DMSO methanol or dichlormethane. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | JVHIPYJQMFNCEK-ZPSJVCBQSA-N |
| Smiles | [H][C@@]1(CC2=CC=CC=C2)NC(=O)[C@]23[C@@]1([H])[C@H](C)C(=C)[C@@H](O)[C@]2([H])\C=C\C[C@H](C)C[C@H](C)\C=C\C3([H])OC(C)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Natural cytochalasin derivative.
- Antiviral. Inhibitor of HIV-1 protease.
- Antifungal activity.
Product References
- L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease: I. The producing organism and its fermentation: A.W. Dombrowski, et al.; J. Antibiot. 45, 671 (1992)
- L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease: II. Isolation and structure: J. Ondeyka, et al.; J. Antibiot. 45, 679 (1992)
- L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease: III. Biological activity: R.B. Lingham, et al.; J. Antibiot. 45, 686 (1992)
- Microbial transformation of L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease: T.S. Chen, et al.; J. Nat. Prod. 56, 755 (1993)
- An enantioselective, modular, and general route to the cytochalasins: Synthesis of L-696,474 and cytochalasin B: A.M. Haidle & A.G. Myers; PNAS 101, 12048 (2004)
- Fungicidal activity of L-696,474 and cytochalasin D from the ascomycete Daldinia concentria against plant pathogenic fungi: L. Du-Qiang, et al.; Acta Phytophyl. Sinica 34, 113 (2007)
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