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Inhibitor of human leukocyte elastase (IC50 = 1.3 μg/ml), different other elastases and chymotrypsin (IC50 = 82 μg/ml).
Product References
Elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces.: S. Omura, et al.; BBRC 83, 704 (1978)
Isolation and characterization of elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces: H. Ohno, et al.; J. Antibiot. 31, 1116 (1978)
Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones.: R.W. Spencer, et al.; J. Med. Chem. 28, 1828 (1985)
Inhibition of human sputum elastase by substituted 2-pyrones.: L. Cook, et al.; J. Med. Chem. 30, 1017 (1987)