BioViotica

Elasnin

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BVT-0342-M0011 mgCHF 155.00

BVT-0342-M0055 mgCHF 470.00

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Product Details
Synonyms	3,5-Dibutyl-4-hydroxy-6-(6-oxoundecan-5-yl)-2H-pyran-2-one
Product Type	Chemical
Properties
Formula	C₂₄H₄₀O₄
MW	392.6
CAS	68112-21-0
Source/Host Chemicals	Isolated from Streptomyces sp.
Purity Chemicals	≥97% (HPLC)
Appearance	Tan to brown viscous liquid.
Solubility	Soluble in DMSO (5 mg/ml), methanol (5 mg/ml) or methylene chloride.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by BioViotica.
InChi Key	SNSPVFCYLPZTRZ-UHFFFAOYSA-N
Smiles	CCCCCC(=O)C(CCCC)C1=C(CCCC)C(O)=C(CCCC)C(=O)O1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light when in solution.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Inhibitor of human leukocyte elastase (IC₅₀ = 1.3 μg/ml), different other elastases and chymotrypsin (IC₅₀ = 82 μg/ml).

Product References

Elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces.: S. Omura, et al.; BBRC 83, 704 (1978)
Isolation and characterization of elasnin, a new human granulocyte elastase inhibitor produced by a strain of Streptomyces: H. Ohno, et al.; J. Antibiot. 31, 1116 (1978)
Inhibition of human leukocyte elastase, porcine pancreatic elastase, and chymotrypsin by elasnin and other 4-hydroxy-2-pyrones.: R.W. Spencer, et al.; J. Med. Chem. 28, 1828 (1985)
Inhibition of human sputum elastase by substituted 2-pyrones.: L. Cook, et al.; J. Med. Chem. 30, 1017 (1987)

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