BioViotica

19-O-Acetylchaetoglobosin A

CHF 115.00
In stock
BVT-0383-M0011 mgCHF 115.00
BVT-0383-M0055 mgCHF 340.00
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Product Details
Product Type Chemical
Properties
Formula

C34H38N2O6

MW 570.7
CAS 50939-69-0
Source/Host Chemicals Isolated from Chaetomium sp.
Purity Chemicals ≥98% (HPLC, NMR)
Appearance Yellow solid.
Solubility Soluble in DMSO, acetone or dichloromethane. Fairly soluble in water or methanol.
Identity Determined by 1H-NMR and MS.
Declaration Manufactured by BioViotica.
InChi Key AZLAYOMQTNEYFJ-PWPDRILLSA-N
Smiles [H][C@]12[C@H](CC3=CNC4=CC=CC=C34)NC(=O)[C@]11C(=O)\C=C\C(=O)[C@H](OC(C)=O)\C(C)=C/[C@@H](C)C\C=C\[C@@]1([H])[C@@H]1O[C@]1(C)[C@H]2C
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice After reconstitution protect from light at -20°C.
Protect from light.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
After reconstitution protect from light at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Cytochalasan alkaloid, derivative of chaetoglobosin A (Prod. No. BVT-0092).
  • Mycotoxin.
  • Phytotoxin.
Product References
  1. 19-O-Acetylchaetoglobosin B and 19-O-Acetylchaetoglobosin D, Two New Metabolites of Chaetomium globosum: A. Probst & C. Tamm; Helv. Chim. Acta 64, 2056 (1981)
  2. Biosynthesis of the cytochalasans. Biosynthetic studies on chaetoglobosin A and 19-O-acetylchaetoglobosin A: A. Probst & C. Tamm; Helv. Chim. Acta 64, 2065 (1981)
  3. Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from Chaetomium spp. I. production, isolation and some cytological effects of chaetoglobosin A-J: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1609 (1982)
  4. Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from chaetomium spp. II Structures of chaetoglobosins A, B, and D: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1618 (1982)
  5. Structure-activity relationship of thirty-nine cytochalasans observed in the effects on cellular structures and cellular event and on actin polymerization in vitro: S. Sekita, et al.; J. Pharmacobio-Dynam. 8, 906 (1985)
  6. Phytotoxic chaetoglobosins are produced by the plant pathogen Calonectria morganii (anamorph Cylindrocladium scoparium): C. Wallbrunn, et al.; J. Gen. Appl. Microbiol. 47, 33 (2001)
  7. Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis: K. Ishiuchi, et al.; JACS 135, 7371 (2013)
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