80 CHF CHF 80.00
BVT-0092-M0011 mgCHF 80.00
BVT-0092-M0055 mgCHF 320.00
|Source/Host Chemicals||Isolated from Chaetomium sp.|
|Purity Chemicals||≥98% (HPLC)|
|Solubility||Soluble in methanol; almost insoluble in water.|
|Identity||Determined by 1H-NMR.|
|Declaration||Manufactured by BioViotica.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Handling Advice||Protect from light.|
Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
|Product Specification Sheet|
- Cytochalasan analog with anti-fungal activity.
- Phytotoxic, nematicidal and anti-bacterial activity.
- Exhibits cytotoxic effects against human cancer cell lines.
- Induces apoptosis in lymphocytic leukemia cells by targeting the cytoskeleton.
- Enhances fibrinolytic activity of bovine aortic endothelial cells.
- Acute toxic effects of chaetoglobosin A, a new cytochalasan compound produced by Chaetomium globosum, on mice and rats: K. Ohtsubo, et al.; Jpn. J. Exp. Med. 48, 105 (1978)
- Chaetoglobosins, cytotoxic 10-(indol-3-yl)-cytochalasans from Chaetomium spp. I. Production, isolation and some cytological effects of chaetoglobosins A-J: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1609 (1982)
- Enhancement of fibrinolytic activity of vascular endothelial cells by chaetoglobosin A, crinipellin B, geodin and triticone B: C. Shinohara, et al.; J. Antibiot. 53, 262 (2000)
- Phytotoxic chaetoglobosins are produced by the plant pathogen Calonectriam organii (anamorph Cylindrocladium scoparium): C. Von Wallbrunn, et al.; J. Gen. Appl. Microbiol. 47, 33 (2001)
- Chaetoglobosins Q, R, and T, three further new metabolites from Chaetomium globosum: W. Jiao, et al.; J. Nat. Prod. 67, 1722 (2004)
- Growth and mycotoxin production by Chaetomium globosum: M.R. Fogle, et al.; Mycopathologia 164, 49 (2007)
- New azaphilones from Chaetomium globosum isolated from the built environment: D. R. McMullin, et al.; Tetrahedron Lett. 54, 568 (2013)
- Combinatorial generation of complexity by redox enzymes in the chaetoglobosin A biosynthesis: K. Ishiuchi, et al.; JACS 135, 7371 (2013)
- Nematicidal activity of chaetoglobosin A produced by Chaetomium globosum NK102 against Meloidogyne incognita: Y. Hu, et al.; J. Agricult. Food Chem. 61, 41 (2013)
- Efficacy assessment of antifungal metabolites from Chaetomium globosum No.05, a new biocontrol agent, against Setosphaeria turcica: G. Zhang, et al.; BioControl 64, 90 (2013)
- Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton: P. B. Knudson, et al.; Leukemia 28, 1289 (2014)
- Production of vineomycin A1 and chaetoglobosin A by Streptomyces sp. PAL114: A. Aouiche, et al.; Ann. Microbiol. 65, 1351 (2015)