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BioViotica
Chaetoglobosin F
215
CHF
CHF 215.00
In stock
BVT-0461-M0011 mgCHF 215.00
| Product Details | |
|---|---|
| Synonyms | (21,22-Dihydro,19-ketone,20β-alcohol)-chaetoglobosin A |
| Product Type | Chemical |
| Properties | |
| Formula |
C32H38N2O5 |
| MW | 530.7 |
| CAS | 55945-75-0 |
| Source/Host Chemicals | Isolated from Chaetomium sp. |
| Purity Chemicals | ≥98% (HPLC, NMR) |
| Appearance | Off-white solid. |
| Solubility | Soluble in DMSO, acetone or dichloromethane. Poorly soluble in methanol. Insoluble in water. |
| Identity | Determined by 1H-NMR and MS. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | KTFGDHPTDQFFRL-WSLWJRNMSA-N |
| Smiles | [H][C@]12[C@H](CC3=CNC4=CC=CC=C34)NC(=O)[C@]11C(=O)CC[C@@H](O)C(=O)\C(C)=C/[C@@H](C)C\C=C\[C@@]1([H])[C@@H]1O[C@]1(C)[C@H]2C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Cytochalasan mycotoxin, derivative of chaetoglobosin A (Prod. No. BVT-0092).
- Phytotoxic.
- Cytotoxic against HCT116 (human colon cancer cells).
- Antibacterial (Ps. aeruginosa).
- Anti-inflammatory and immunomodulatory compound.
Product References
- Chaetoglobosins, cytotoxic 10-(indol-3-yl)-[13]cytochalasans from Chaetomium spp. I. Production, isolation, and some cytological effects of chaetoglobosin A-J: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1609 (1982)
- Chaetoglobosins, cytotoxic 10-(indol-3yl)-[13]cytochalasans from Chaetomium spp. III. Structures of chaetoglobosins C, E, F, G, and J: S. Sekita, et al.; Chem. Pharm. Bull. 30, 1629 (1982)
- Chaetoglobosin U, a cytochalasan alkaloid from endophytic Chaetomium globosum IFB-E019: G. Ding, et al.; J. Nat. Prod. 69, 302 (2006)
- Cytotoxic 10-(indol-3-yl)-[13]cytochalasans from the fungus Chaetomium elatum ChE01: S. Thohinung, et al.; Arch. Pharm. Res. 33, 1135 (2010)
- Cytotoxic chaetoglobosins from the endophyte Chaetomium globosum: J. Zhang, et al.; Planta Med. 76, 1910 (2010)
- New azaphilones from Chaetomium globosum isolated from the built environment: D.R. McMullin, et al.; Tetrahedron Lett. 54, 568 (2013)
- Chaetoglobosin F, a small molecule compound, possesses immunomodulatory properties on bone marrow-derived dendritic cells via TLR9 signaling pathway: C. Hua, et al.; Immunobiology 218, 292 (2013)
- Chaetoglobosins and azaphilones produced by Canadian strains of Chaetomium globosum isolated from the indoor environment: D.R. Mcmullin, et al.; Mycotoxin Res. 29, 47 (2013)
- Production of an antimicrobial cytochalasan by an endophytic Chaetomium globosum HYML55 from Hypericum mysorense and its RNA secondary structure analysis: P. Samaga, et al.; Chem. Ecology 30, 566 (2014)
- Chaetoglobosins from Chaetomium globosum, an endophytic fungus in Ginkgo biloba, and their phytotoxic and cytotoxic activities: H. Li, et al.; J. Agr. Food Chem. 62, 3734 (2014)
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