Cytochalasin J

CHF 120.00
In stock
BVT-0450-M0011 mgCHF 120.00
BVT-0450-M0055 mgCHF 420.00
 
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Product Details
Synonyms Deacetylcytochalasin H; Kodocytochalasin 2; Paspalin P II
Product Type Chemical
Properties
Formula C28H37NO4
MW 451.6
CAS 53760-20-6
RTECS HA5320000
Source/Host Chemicals Isolated from Phomopsis sp.
Purity Chemicals ≥98% (NMR)
Appearance White solid.
Solubility Soluble in DMSO or water.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key UKQNIEMKORIOQM-ITYZSRHZSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light when in solution.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Mycotoxin.
  • Phytotoxic and cytotoxic agent.
  • Immunosuppressive activity.
  • Affects chromosome congression and spindle microtubule organization in PtK1 cells.
  • Actin and myosin inhibitor.
Product References
  1. Isolation and biological properties of deacetylcytochalasin H from Phomopsis sp.: R.J. Cole, et al.; J. Agric. Food Chem. 29, 205 (1981)
  2. A new immunosuppressive cytochalasin isolated from a Pestalotia sp.: N.S. Burres, et al.; J. Antibiot. 45, 1367 (1992)
  3. Cytochalasin J affects chromosome congression and spindle microtubule organization in PtK1 cells: J.A. Snyder, et al.; Cell Motil. Cytoskel. 32, 245 (1995)
  4. The effect of cytochalasin J on kinetochore structure in PTK1 cells is mitotic cycle dependent: G.A. Wrench & J.A. Snyder; Cell Biol. Int. 25, 815 (2001)
  5. Redistribution of motor proteins by cytochalasin J treatment: R.W. Robinson & J.A. Snyder; Cell Biol. Int. 27, 665 (2003)
  6. Colocalization studies of Arp1 and p150Glued to spindle mircotubules during mitosis: the effect of cytochalasin J on the organization of microtubules and motor proteins in PtK1 cells: R.W. Robinson, et. al.; Cell Biol. Int. 30, 631 (2006)
  7. Cytotoxic cytochalasin metabolites of endophytic Endothia gyrosa: S. Xu, et al.; Chem. Biodiv. 6, 739 (2009)
  8. Both actin and myosin inhibitors affect spindle architecture in PtK1 cells: J.A. Snyder, et al.; Protoplasma 240, 57 (2010)
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