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BioViotica
Pikromycin
95
CHF
CHF 95.00
In stock
BVT-0400-M0011 mgCHF 95.00
BVT-0400-M0055 mgCHF 290.00
| Product Details | |
|---|---|
| Synonyms | Picromycin; Amaromycin; Antibiotic B 62169A; Albomycetin |
| Product Type | Chemical |
| Properties | |
| Formula |
C28H47NO8 |
| MW | 525.7 |
| CAS | 19721-56-3 |
| Source/Host Chemicals | Isolated from Streptomyces sp. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | White crystalline solid. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | UZQBOFAUUTZOQE-AKYJXTIJSA-N |
| Smiles | CC[C@H]1OC(=O)[C@H](C)C(=O)[C@H](C)[C@@H](O[C@@H]2OC(C)C[C@H](C2O)N(C)C)[C@@H](C)C[C@@H](C)C(=O)\C=C\[C@]1(C)O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic. 14-Membered macrolide.
- Active against Gram-positive bacteria including mycobacteria.
- Prolyl endopeptidase (PREP) inhibitor.
Product References
- Pikromycin, ein neues Antibiotikum aus Actinomyceten: H. Brockmann & W. Henkel; Naturwissenschaften 37, 138 (1950)
- Pikromycin, ein bitter schmeckendes antibioticum aus Actinomyceten: H. Brockmann & W. Henkel; Chem. Ber. 84, 284 (1951)
- The crystal and molecular structure of Pikromycin: A. Furusaki, et al.; Bull. Chem. Soc. Jpn. 55, 59 (1982)
- Albocycline- and carbomycin-type macrolides, inhibitors of human prylol endopeptidases: C. Christner, et al.; J. Antibiot. 51, 368 (1998)
- The Methymycin/pikromycin pathway: A model for metabolic diversity in natural product biosynthesis: J. D. Kittendorf & D. H. Sherman; Bioorg. Med. Chem. 17, 2137 (2009)
- Total synthesis of Pikromycin: H.-S. Oh & H.-Y. Kang; J. Org. Chem. 77, 1125 (2012)
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