Chaetoviridin A

CHF 150.00
In stock
BVT-0419-M0011 mgCHF 150.00
BVT-0419-M0055 mgCHF 560.00
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Product Details
Synonyms CCRIS 7226
Product Type Chemical
Properties
Formula

C23H25ClO6

MW 432.9
CAS 128252-98-2
Source/Host Chemicals Isolated from Chaetomium sp.
Purity Chemicals ≥96% (HPLC)
Appearance Yellow to orange powder.
Solubility Soluble in DMSO, methanol, chloroform or acetone.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
InChi Key HWSQVPGTQUYLEQ-LYUOGRNPSA-N
Smiles O=C1C(C([C@H](C)[C@@H](C)O)=O)=C2C3=COC(/C=C/[C@@H](C)CC)=CC3=C(Cl)C([C@@]2(C)O1)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Azaphilone antibiotic.
  • Antifungal compound (phytopathogenic fungi).
  • Cholesteryl ester transfer protein (CETP) inhibitor. Improves blood lipid levels.
  • Monoamine oxidase inhibitor.
Product References
  1. Four new azaphilones from Chaetomium globosum var. flavor-viridae: M. Takahashi, et al.; Chem. Pharm. Bull. 38, 625 (1990)
  2. Structure-specific inhibition of cholesteryl ester transfer protein by azaphilones: H. Tomoda, et al.; J. Antibiot. 52, 160 (1999)
  3. Antifungal activity against plant pathogenic fungi of chaetoviridins isolated from Chaetomium globosum: J.-H. Park, et al.; FEMS Microbiol. Lett. 252, 309 (2005)
  4. Bis-spiro-azaphilones and azaphilones from the fungi Chaetomium cochliodes VTh01 and C. cochliodes CTh05: N. Phonkerd, et al.; Tetrahedron 64, 9636 (2008)
  5. Azaphilones, a class of fungal metabolites with diverse biological activities: N. Osmanova, et al.; Phytochem. Rev. 9, 315 (2010)
  6. Azaphilones from the endophyte Chaetomium globosum: W. S. Borges, et al.; J. Nat. Prod. 74, 1182 (2011)
  7. Identification and characterization of the chaetoviridin and chaetomugilin gene cluster in Chaetomium globosum: J. M. Winter, et al.; JACS 134, 17900 (2012)
  8. New azaphilones from Chaetomium globosum isolated from the built environment: D. R. McMullin, et al.; Tetrahedron Lett. 54, 568 (2013)
  9. Potentially harmful secondary metabolites produced by indoor Chaetomium species on artificially and naturally contaminated building materials: I. Dosen, et al.; Indoor Air 27, 34 (2017)
  10. Total Synthesis and Structural Revision of Chaetoviridins A: M. Makrerougras, et al.; Org. Lett. 19, 4146 (2017)
  11. New metabolites from endophytic fungus Chaetomium globosum CDW7: W. Yan, et al.; Molecules 23, 2873 (2018)
  12. The screening and identification of the biological control fungi Chaetomium spp. against wheat common root rot: H.-M. Yue, et al.; FEMS Microbiol. Lett. 365, fny242 (2018)
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