BVT-0413-M0011 mgCHF 90.00
|Synonyms||5- Methylochracin; 3,4-Dihydro-8-hydroxy-3,5-dimethyl-1H-2-benzopyran1- one; 3,4-Dihydro-8-hydroxy-3,5-dimethylisocoumarin|
|Source/Host Chemicals||Isolated from Fusicoccum amygdalis.|
|Purity Chemicals||≥98% (HPLC)|
|Appearance||Pale yellow powder.|
|Solubility||Soluble in DMSO, chloroform or dichloromethane.|
|Identity||Determined by 1H-NMR.|
|Declaration||Manufactured by BioViotica.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
|Handling Advice||Protect from light when in solution.|
Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
|Product Specification Sheet|
- Widespread fungal pentaketide.
- Weak antibacterial, antifungal and antiviral activity.
- Specific inhibitor of human DNA polymerase λ.
- Weak antigerminative activity.
- 5-Methylmellein, a new natural dihydroisocoumarin: A. Ballio, et al.; Tetrahedron Lett. 1966, 3723 (1966)
- (-)-5-Methylmellein and catechol derivatives from four semecarpus species: R.C. Carpenter, et al.; Phytochemistry 19, 445 (1980)
- 3-Methyl-3,4-dihydroisocoumarins and related compounds from the ascomycete family xylariaceae: J.R. Anderson & R.L. Edwards; J. Chem. Soc. Perkin Trans I 1983, 2185 (1983)
- Dihydroisocoumarins from fungi: isolation, structure elucidation, circular dichroism and biological activity: K. Krohn, et al.; Phytochemistry 45, 313 (1997)
- Nodulisporol and nodulisporone, novel specific inhibitors of human DNA polymerase λ from a fungus, Nodulisporium sp.: S. Kamisuki, et al.; Bioorg. Med. Chem. 15, 3109 (2007)
- Bioactive aromatic derivatives from endophytic fungus, Cytospora sp.: S. Lu, et al.; Nat. Prod. Commun. 6, 661 (2011)
- Guaiane sesquiterpenes from Biscogniauxia nummularia featuring potent antigerminative activity: S. Amand, et al.; J. Nat. Prod. 75, 798 (2012)