CHF 115.00
In stock
BVT-0404-M0011 mgCHF 115.00
BVT-0404-M0055 mgCHF 340.00
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Product Details
Synonyms 3,28-di(diMeG)betulin; NSC705961; Betulin 3,28-(3,3-dimethyl)glutarate
Product Type Chemical


MW 727.0
Source/Host Chemicals Semi-synthetic derivative from betulin (from birch bark).
Purity Chemicals ≥97% (HPLC)
Appearance White to off-white solid. This substance is hygroscopic and might gradually change its state of aggregation from solid to oil.
Solubility Soluble in methanol, acetone or DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
Smiles [H][C@]12[C@@H](CCC1(COC(=O)CC(C)(C)CC(O)=O)CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)CC(C)(C)CC(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(C)=C
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Very hygroscopic.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Semi-synthetic derivative of betulin (from birch bark).
  • Potent antiviral compound.
  • Shows anti-HIV activity (more active than AZT in vitro).
Product References
  1. Anti-AIDS agents. 32. Synthesis and anti-HIV activity of betulin derivatives: I.-C. Sun, et al.; Bioorg. Med. Chem. Lett. 8, 1267 (1998)
  2. Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents: I.-C. Sun, et al.; J. Med. Chem. 41, 4648 (1998)
  3. 3,28-Di-O-(dimethylsuccinyl)-betulin isomers as anti-HIV agents: Y. Kashiwada, et al.; Bioorg. Med. Chem. Lett. 11, 183 (2001)
  4. 3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents: Y. Kashiwada, et al.; Bioorg. Med. Chem. Lett. 14, 5851 (2004)
  5. Birch bark research and development: P.A. Krasutsky; Nat. Prod. Rep. 23, 919 (2006)
  6. Pharmacological properties of the ubiquitous natural product betulin: S. Alakurtti, et al.; Eur. Pharm. Sci. 29, 1 (2006)
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