115 CHF CHF 115.00
BVT-0404-M0011 mgCHF 115.00
BVT-0404-M0055 mgCHF 340.00
|Synonyms||3,28-di(diMeG)betulin; NSC705961; Betulin 3,28-(3,3-dimethyl)glutarate|
|Source/Host Chemicals||Semi-synthetic derivative from betulin (from birch bark).|
|Purity Chemicals||≥97% (HPLC)|
|Appearance||White to off-white solid. This substance is hygroscopic and might gradually change its state of aggregation from solid to oil.|
|Solubility||Soluble in methanol, acetone or DMSO.|
|Identity||Determined by 1H-NMR.|
|Declaration||Manufactured by BioViotica.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||-20°C|
Keep cool and dry.
Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
|Product Specification Sheet|
- Semi-synthetic derivative of betulin (from birch bark).
- Potent antiviral compound.
- Shows anti-HIV activity (more active than AZT in vitro).
- Anti-AIDS agents. 32. Synthesis and anti-HIV activity of betulin derivatives: I.-C. Sun, et al.; Bioorg. Med. Chem. Lett. 8, 1267 (1998)
- Anti-AIDS agents. 34. Synthesis and structure-activity relationships of betulin derivatives as anti-HIV agents: I.-C. Sun, et al.; J. Med. Chem. 41, 4648 (1998)
- 3,28-Di-O-(dimethylsuccinyl)-betulin isomers as anti-HIV agents: Y. Kashiwada, et al.; Bioorg. Med. Chem. Lett. 11, 183 (2001)
- 3-O-Glutaryl-dihydrobetulin and related monoacyl derivatives as potent anti-HIV agents: Y. Kashiwada, et al.; Bioorg. Med. Chem. Lett. 14, 5851 (2004)
- Birch bark research and development: P.A. Krasutsky; Nat. Prod. Rep. 23, 919 (2006)
- Pharmacological properties of the ubiquitous natural product betulin: S. Alakurtti, et al.; Eur. Pharm. Sci. 29, 1 (2006)