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BioViotica
Roquefortine C
115
CHF
CHF 115.00
In stock
BVT-0425-C500500 µgCHF 115.00
BVT-0425-M0011 mgCHF 205.00
| Product Details | |
|---|---|
| Synonyms | NSC292134 |
| Product Type | Chemical |
| Properties | |
| Formula |
C22H23N5O2 |
| MW | 389.5 |
| CAS | 58735-64-1 |
| RTECS | UQ4730500 |
| Source/Host Chemicals | Isolated from Penicillium sp. |
| Purity Chemicals | ≥98% (HPLC, NMR) |
| Appearance | White to off-white solid. |
| Solubility | Soluble in DMSO, methanol, 100% ethanol, dimethylformamide, acetone, chloroform or dichloromethane. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | SPWSUFUPTSJWNG-JJUKSXGLSA-N |
| Smiles | [H][C@@]12C[C@]3(C4=CC=CC=C4N[C@@]3([H])N1C(=O)\C(NC2=O)=C/C1=CN=CN1)C(C)(C)C=C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Potent neurotoxin.
- Mycotoxin.
- Tremorgenic.
- Gram-positive bacteria growth inhibitor.
- Cytochrome p450 inhibitor.
- Lymphocyte proliferation inhibitor.
- Cytotoxic.
Product References
- Isolation of festuclavine and three new indole alkaloids, roquefortine A, B and C from the cultures of Penicillium roqueforti: S. Ohmomo, et al.; Agric. Biol. Chem. 39, 1333 (1975)
- Roquefortine and isofumigaclavine A, metabolites from Penicillium roqueforti: P.M. Scott, et al.; Experientia 32, 140 (1976)
- Identification of roquefortine C produced by Penicillium roqueforti: S. Ohmomo et al.; Agric. Biol. Chem. 41, 2097 (1977)
- Antimicrobial action of roquefortine: B. Kopp-Holtwiesche & H.J. Rehm; J. Environ. Pathol. Toxicol. Oncol. 10, 41 (1990)
- MS/MS screen for the tremorgenic mycotoxins roquefortine and penitrem A: W.E. Braselton & P.C. Rumler; J. Vet. Diagn. Invest. 8, 515 (1996)
- Molecular requirements for inhibition of cytochrome p450 activities by roquefortine: C. Aninat, et al.; Chem. Res. Toxicol. 14, 1259 (2001)
- The effects of the Penicillium mycotoxins citrinin, cyclopiazonic acid, ochratoxin A, patulin, penicillic acid, and roquefortine C on in vitro proliferation of porcine lymphocytes: M. Keblys, et al.; Mycopathologia 158, 317 (2004)
- Combined effects of selected Penicillium mycotoxins on in vitro proliferation of porcine lymphocytes: A. Bernhoft, et al.; Mycopathologia 158, 441 (2004)
- Cytotoxicity of occupationally and environmentally relevant mycotoxins: J. Bunger, et al.; Toxicology 202, 199 (2004)
- Application of Ambient Ionization Mass Spectrometry to Detect the Mycotoxin Roquefortine C in Blue Cheese: C.M. Maragos; Food Analyt. Meth. 45, (2021)
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