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BioViotica
Trypacidin
130
CHF
CHF 130.00
In stock
BVT-0442-M0011 mgCHF 130.00
BVT-0442-M0055 mgCHF 395.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C18H16O7 |
| MW | 344.3 |
| CAS | 1900-29-4 |
| RTECS | WG9780000 |
| Source/Host Chemicals | Isolated from Aspergillus fumigatus. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white solid. |
| Solubility | Soluble in DMSO, acetone or dichloromethane. |
| Identity | Determined by 1H-NMR, MS and optical rotation. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | KMZYINVXZDQCKC-GOSISDBHSA-N |
| Smiles | COC(=O)C1=CC(=O)C=C(OC)[C@]11OC2=C(C1=O)C(OC)=CC(C)=C2 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light when in solution. |
| Use/Stability |
Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Antibacterial and antiprotozoal (trypanocidal).
- Toxic to human A549 lung cells.
- Necrosis inducer.
- Toxic to human bronchial epithelial cells.
- Stimulating the growth of corn seedling roots.
- Inhibits IL-6 secretion, collagen IV and fibronectin production
Product References
- Antiprotozoal antibiotics. II. Isolation and characterization of trypacidin, a new antibiotic, active against Trypanosoma cruzi and Toxoplasma gondii: J. Balan, et al.; J. Antibiot. 16, 157 (1963)
- Trypacidin a new protozoal antibiotic: J. Balan, et al.; Naturwissenschaften 5, 227 (1964)
- The structure of Trypacidin: J. Balan, et al.; Acta Chem. Scand. 19, 528 (1965)
- Growth of Trypanosoma cruzi in human heart tissue cells and effects of aminonucleoside of puromycin, trypacidin and aminopterin: W.E. Gutteridge, et al.; J. Protozool. 16, 521 (1969)
- Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cells: T. Gauthier, et al.; PLoS One 7, e29906 (2012)
- Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity: E. Pinheiro, et al.; An. Acad. Bras. Cienc. 85, 1247 (2013)
- Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy: Y. Yang, et al.; Bioorg. Med. Chem. Let. 23, 3905 (2013)
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