6-(4-Acetamido-1,8-naphthalamido) hexanoic acid

CHF 70.00
In stock
CDX-A0038-M01010 mgCHF 70.00
CDX-A0038-M05050 mgCHF 186.00
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Product Details
Product Type Chemical
Properties
Formula

C20H20N2O5

MW 368.38
CAS 172227-59-7
Source/Host Chemicals Synthetic.
Purity Chemicals ≥95% (HPCE)
Appearance Solid.
Solubility Soluble in water or DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key RCZAYEHQRFPFSH-UHFFFAOYSA-N
Smiles CC(=O)NC1=CC=C2C(=O)N(CC(O)=O)C(=O)C3=C2C1=CC=C3
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

The highly fluorescent label 4-acetylamino-1,8-naphthalimide-N-caproic acid has two fused benzene rings containing a closed anhydride ring and therefore is a flat and planar molecule which can easily intercalate or act as a groove binder with DNA/RNA sequences. For the study of in situ hydridization with complementary synthetic oligonucleotides (ODNs), tagging with non-radioactive labels has gained importance, not only for medical diagnostics or clinical genetics, but also detection and isolation of DNA for research purposes. The pentamethylene chain in 6 acts as a linker molecule and keeps the target at a reasonable distance to avoid direct interaction with oligonucleotides.

Product References

(1) K. Misra et al.; Radiobiol. Bio-Med. Res., 129 (2004) | (2) R.W. Odd et al.; Blackwell Scientific Publication, 317 (1992) | (3) R.J. Kaiser et al.; Nucleic Acids Research 17, 6087 (1989)

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