Actinomycin D

CHF 199.00
In stock
CDX-A0043-M02020 mgCHF 199.00
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Product Details
Synonyms 2-Amino-N,N'-bis[(6S,9R,10S,13R,18aS)-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxohexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-3H-phenoxazin e-1,9-dicarboxamide
Product Type Chemical


MW 1255.42
CAS 50-76-0
Purity Chemicals ≥95% (HPLC)
Appearance Red to orange solid.
Solubility Soluble in acetone or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

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Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
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Product Specification Sheet
Datasheet Download PDF

Biochemical/physiological actions: An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes.

Product References

(1) H. Li et al., Bioorg. Med. Chem. 14(12), 4089 (2006) | (2) C. Liu et al.; Biochem. 35(50), 16346 (1996) | (3) J.A. Neidhart et al.; Cancer Treatment Reports 64(4-5), 553 (1980)

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