Chemodex

4'-(Aminomethyl)fluorescein hydrochloride

Name: 4'-(Aminomethyl)fluorescein hydrochloride
Brand: Chemodex
SKU: CDX-A0075
Price: 187.00 CHF
Availability: InStock

As low as CHF 187.00

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CDX-A0075-M02525 mgCHF 187.00

CDX-A0075-M100100 mgCHF 561.00

Specifications / Handling

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Product Details
Synonyms	4-AMF; 4'-((Aminoacetamido)methyl)fluorescein
Product Type	Chemical
Properties
Formula	C₂₁H₁₆ClNO₅
MW	397.81
CAS	91539-64-9
Source/Host Chemicals	Synthetic
Purity Chemicals	≥97% (HPLC)
Appearance	Orange solid.
Solubility	Soluble in DMSO.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	JJYRABHKUBHHSU-UHFFFAOYSA-N
Smiles	OC1=CC=C(C(C2=CC=CC=C2C(O)=O)=C(C=C3)C(O4)=C(CN)C3=O)C4=C1.Cl
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	-20°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

4'-(Aminomethyl)fluorescein is an excellent building block for developing fluoresceinated bioconjugates. Its amino group readily reacts with activated carboxy esters (such as NHS ester). The primary aliphatic amine of 4'-(aminomethyl)fluorescein can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNBH3) to form new probes. Carboxylic acids of proteins and other water-soluble biopolymers can be coupled to this molecule in aqueous solution using water-soluble carbodiimides such as EDAC. Spectral Data: λex 494 nm; λem 520 nm.

Product-specific References

(1) M.T. Shipchandler, et al.; Anal. Biochem. 162, 89 (1987) | (2) R. Dhar Dubey, et al.; Nanotheranostics 1, 59 (2017)

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