Chemodex

Adenine

CHF 81.00
In stock
CDX-A0083-G02525 gCHF 81.00
CDX-A0083-G100100 gCHF 244.00
More Information
Product Details
Synonyms 6-Aminopurine; Vitamin B4
Product Type Chemical
Properties
Formula

C5H5N5

MW 135.13
CAS 73-24-5
RTECS AU6125000
Purity Chemicals ≥98% (NMR)
Appearance White to off-white solid.
Solubility Soluble methanol or ethanol. Slightly soluble in water (~1mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key GFFGJBXGBJISGV-UHFFFAOYSA-N
Smiles NC1=NC=NC2=C1N=CN2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at RT.
Documents
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Product Specification Sheet
Datasheet Download PDF
Description

Adenine is a purine nucleobase. It is part of DNA and RNA and is also a component of cofactors (NAD, FAD) and signaling molecules (cAMP). Adenine is essential for many in vivo and in vitro biochemical processes. Adenine is converted to adenosine with ribose. On phosphorylation, it forms AMP, ADP and ATP. ATP is the energy currency of the cell and is required during cellular metabolism. Adenine is metabolized to 2,8-dihydroxyadenine, which on accumulation in proximal tubules leads to the induction of chronic kidney disease (CKD) with severe anemia in rats. Adenine based derivatives elicit antiviral functionality against dsDNA viruses and are exploited for generating antiviral scaffolds. Adenine is suitable for use as a media nucleic acid base supplement in cell culture or food/dietary research.

Product References

(1) G. Nuki; Ann. Rheum. Dis. 42, 8 (1983) | (2) R. Shapiro; Orig. Life Evol. Biosph. 25, 83 (1995) | (3) J. Ross; J. Phys. Chem. B 110, 6987 (2006) | (4) T.E. Parry; Leuk. Res. 31, 1621 (2007) | (5) D. Thimm, et al.; Acta Physiol. 213, 808 (2015) | (6) C. Wang, et al.; Acta Pharm. Sin. B. 5, 431 (2015)

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