Chemodex

8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt

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Specifications / Handling

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Product Details
Synonyms APTS; 1,3,6-Pyrenetrisulfonic acid, 8-amino trisodium salt; Trisodium 8-aminopyrene-1,3,6-trisulfonate
Product Type Chemical
Properties
Formula C16H8NNa3O9S3
MW 523.4
CAS 196504-57-1
Source/Host Chemicals Synthetic
Purity Chemicals ≥96% (HPLC)
Appearance Yellow to dark yellow powder.
Solubility Soluble in water (10mg/ml), DMF or DMSO (1mg/ml).
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key XSTNYACEWLNWPY-UHFFFAOYSA-K
Smiles [Na+].[Na+].[Na+].Nc1cc(c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O)S([O-])(=O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
Product Specification Sheet
Datasheet Download PDF Download PDF

Scientific Background Information

Product Description
8-Aminopyrene-1,3,6-trisulfonic acid (APTS) is an anionic fluorescent dye. It forms a ground state complex with viologen-type quenchers, inducing a red-shift in the absorbance spectrum from 425 to 464 nm. APTS is pH insensitive, with the emission maximum remaining constant over the pH range of 4-10. APTS is a highly fluorescent labeling reagent widely used for glycan and carbohydrate analysis. Through reductive amination, APTS efficiently labels reducing sugars, enabling sensitive detection and high-resolution separation by capillary electrophoresis with laser-induced fluorescence (CE-LIF). Spectral Data: Ex/Em maxima 425/503 nm (in pH 7.4 PBS).
Product-specific References
(1) R.A. Evangelista, et al.; Electrophoresis 17, 347 (1996) | (2) Y. Yoshinaka, et al.; J.Chromatogr. 1143, 83 (2007) | (3) Z. Sharrett, et al.; Org. Biomol. Chem. 7, 1461 (2009) | (4) P. Smejkal, et al.; Electrophoresis 31, 3783 (2010) | (5) D.B. Cordes & B. Singaram; Pure Appl. chem. 84, 2183 (2012) | (6) S.C. Bunz, et al.; Anal. Bioanal. Chem. 405, 8277 (2013) | (7) H.T. Feng, et al.; Electrophoresis 38, 1788 (2017) | (8) S. Yamamoto, et al.; J. Chromatogr. A. 1566, 44 (2018) | (9) J. Krenkova, et al.; Electrophoresis 42, 1333 (2021) | (10) Y. Deng, et al.; J. Pharm. Anal. 13, 201 (2023) | (11) J.M. Garber, et al.; Methods Mol. Biol. 2657, 223 (2023)
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