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Chemodex
Azure B
As low as
129
CHF
CHF 129.00
In stock
Only %1 left
CDX-A0164-G0055 gCHF 129.00
CDX-A0164-G02525 gCHF 516.00
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Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | C.I. 52010; Trimethylthionine; Azure I; Methylene azure; 3-Methylamino-7-dimethylaminophenazathionium chloride |
| Product Type | Chemical |
| Properties | |
| Formula | C15H16ClN3S |
| MW | 305.83 |
| CAS | 531-55-5 |
| RTECS | SO5550000 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥80% (Dye content) |
| Appearance | Dark green powder. |
| Solubility | Soluble in water (1 mg/ml). Sparingly soluble in ethanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | DNDJEIWCTMMZBX-UHFFFAOYSA-N |
| Smiles | C[N+](C)=C(C=C1)C=C(C1=N2)SC3=C2C=CC(NC)=C3.[Cl-] |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
Azure B is a cationic thiazine dye widely used in histology, cytology and microbiology for biological staining applications. It is commonly employed as a component of Romanowsky-type stains, including Giemsa and related staining systems, where it contributes to the selective coloration of cellular structures and nucleic acids. Known for its strong chromatic properties and reliable staining performance, Azure B is used in the visualization of blood smears, tissue sections, and microbial preparations. Its compatibility with other thiazine dyes, such as methylene blue and Azure A, makes it an important reagent for differential staining protocols in diagnostic and research laboratories. Spectral Data: λex 648 (in ethanol). Azure B is also a high-potency, selective and reversible inhibitor of monoamine oxidases (MAO)-A. It is the main Metabolite of methylene blue.
Product-specific References
(1) W. Lohr, et al.; Stain Technol. 50, 149 (1975) | (2) M.K. Dutt; Microsc. Acta. 83, 403 (1980) | (3) D.H. Wittekind, et al.; Br. J. Haematol. 51, 391 (1982) | (4) D. Wittekind & E. Schulte; Clin. Lab. Haematol. 9, 395 (1987) | (5) F.S. Archibald; Appl. Environ. Microbiol. 58, 3110 (1992) | (6) B. Koch, et al.; Biotech. Histochem. 70, 267 (1995) | (7) D.P. Penney, et al.; Biotech. Histochem. 77, 237 (2002) | (8) A. Petzer, et al.; Toxicol. Appl. Pharmacol. 258, 403 (2012) | (9) A. Delport, et al.; Life Sci. 117, 56 (2014) | (10) L.O. Kostjukova, et al.; J. Mol. Graph. Model. 107, 107964 (2021)