Chemodex

Acetamiprid-d3

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Specifications / Handling

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Product Details
Synonyms d3-Acetamiprid; (E)-N-(6-Chloro-3-pyridylmethyl)-N'-cyano-N-(methyl-d3)acetamidine
Product Type Chemical
Properties
Formula C10H8ClD3N4
MW 225.7
CAS 1353869-35-8
Source/Host Chemicals Synthetic
Purity Chemicals ≥98% (HPLC)
Appearance White to off-white powder or crystals.
Solubility Soluble in chloroform, DMSO or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key WCXDHFDTOYPNIE-BMSJAHLVSA-N
Smiles ClC1=CC=C(CN(C(C)=NC#N)C([2H])([2H])[2H])C=N1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
Product Specification Sheet
Datasheet Download PDF Download PDF

Scientific Background Information

Product Description
Acetamiprid is a neonicotinoid insecticide that acts as an agonist of insect nicotinic acetylcholine receptors (nAChRs). Formulations containing acetamiprid have been used to control sucking insects on crops and pets. Acetamiprid-d3 is a deuterium-labeled analog of acetamiprid with similar activity. This stable isotope-labeled compound contains three deuterium atoms and is commonly utilized as an internal standard in quantitative analytical methods, including LC-MS/MS and GC-MS assays for pesticide residue detection, environmental monitoring, food safety testing, and pharmacokinetic studies. The isotopic labeling enables accurate correction for sample preparation variability, matrix effects, and instrument fluctuations, improving the precision and reliability of quantitative analyses. Acetamiprid-d3 exhibits physicochemical properties nearly identical to those of the native compound while being readily distinguishable by mass spectrometry.
Product-specific References
(1) M. Tomizawa & J.E. Casida; Annu. Rev. Pharmacol. Toxicol. 45, 247 (2005) (Review) | (2) C. Hao, et al.; Rapid Commun. Mass Spectrom. 29, 2225 (2015) | (3) H. Terayama, et al.; Int. J. Environ. Health Res. 28, 683 (2018) | (4) L. Zuscikova, et al.; Toxics 11, 598 (2023) (Review)
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