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Chemodex
L-Alanyl-L-glutamine
54
CHF
CHF 54.00
In stock
CDX-A0222-G01010 gCHF 54.00
CDX-A0222-G05050 gCHF 204.00
| Product Details | |
|---|---|
| Synonyms | Ala-Gln; L-Ala L-Gln; Alanyl-glutamine; Glutamine-S |
| Product Type | Chemical |
| Properties | |
| Formula |
C8H15N3O4 |
| MW | 217.22 |
| CAS | 39537-23-0 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in water (20 mg/ml), ethanol (20mg/ml), DMSO or DMF (30mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | HJCMDXDYPOUFDY-ROLXFIACSA-N |
| Smiles | NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine (Ala-Gln) and Gylcyl-L-glutamine (Gly-Gln) are used in cell culture media as alternative delivery forms of stabilized L-glutamine. Alanyl-glutamine is a widely used alternative supplement to L-glutamine in the production of biopharmaceuticals, cosmetics and food products. Alanyl-glutamine also acts as an antioxidant (peroxide) and anti-apoptosis (LPS-induced) factor. Ala-Gln has been used in studies on injury and sepsis, and on the effects of irradiation on leucine and protein metabolism in vivo. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro. Shown to improve intestinal health and enhances the immune system. It is also involved in various clinical studies such as cancer treatment, radiation and chemotherapy. It improves pancreatic beta-cell function, maintaining the mitochondrial metabolism and stimulus-secretion coupling essential for insulin release.
Product References
(1) P.G. Boelens, et al.; Am. J. Physiol. Endocrinol. Metab. 291, E683 (2006) | (2) Y. Imamoto, et al.; Cytotechnology 65, 135 (2013) | (3) E.R. Petry, et al.; Life Sci. 94, 130 (2014) | (4) V.F. Cruzat, et al.; Nutrition 30, 602 (2014) | (5) M.V. Nova, et al.; Drug Dev. Ind. Pharm. 40, 1308 (2014) | (6) G. Wang, et al.; Ind. Eng. Chem. Res. 53, 3385 (2014) | (7) V.F. Cruzat, et al.; J. Endocrinol. 224, 261 (2015)