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Chemodex
S-Adenosylhomocysteine
As low as
155
CHF
CHF 155.00
In stock
Only %1 left
CDX-A0249-M05050 mgCHF 155.00
CDX-A0249-M100100 mgCHF 271.00
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Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | SAH; S-(5′-Adenosyl)-L-homocysteine; S-Adenosyl-L-homocysteine; 5′-Deoxy-S-adenosyl-L-homocysteine; AdoHcy; S-(5′-Deoxyadenosine-5′)-L-homocysteine |
| Product Type | Chemical |
| Properties | |
| Formula | C14H20N6O5S |
| MW | 384.41 |
| CAS | 979-92-0 |
| Source/Host Chemicals | Enzymatic |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White crystalline powder. |
| Solubility | Soluble in 1M HCl (20mg/ml) or DMSO. Limited soluble in water (1mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | ZJUKTBDSGOFHSH-WFMPWKQPSA-N |
| Smiles | O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CSCC[C@@H](C(O)=O)N)[C@H]1O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
S-Adenosylhomocysteine (SAH) is a naturally occurring metabolite generated during methylation reactions following the transfer of a methyl group from S-adenosylmethionine (SAM). SAH is an amino acid derivative and an intermediate, by-product, or modulator of several metabolic pathways, including the activated methyl cycle and cysteine biosynthesis. It is also a product of S-adenosyl-methionine (SAM)-dependent methylation of biological molecules, including DNA, RNA, and histones and other proteins. As a potent inhibitor of methyltransferases, SAH plays an important role in the regulation of cellular methylation processes. SAH is widely used in epigenetics, methylation research, enzymology studies, and assay development involving methyltransferase activity. SAH is a risk factor for many diseases, including cancer and neurodegenerative diseases. In addition, inhibitors that block its hydrolysis are being developed as anti-viral, anti-parasitic, anti-arthritic and immunosuppressive agents. This compound is used in epigenetics research, methyltransferase assays, enzyme inhibition studies, and metabolic pathway analysis.
Product-specific References
(1) J.D. Finkelstein; Clin. Chem. Lab. Med. 45, 1694 (2007) (Review) | (2) C. Wagner & M.J. Koury; Am. J. Clin. Nutr. 86, 1581 (2007) | (3) Y. Xiao, et al.; Int. J. Biochem. Cell Biol. 67, 158 (2015) (Review) | (4) A. Kuty, et al.; Biomedicines 14, 632 (2026) (Review)