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Chemodex
D-Aspartic acid
54
CHF
CHF 54.00
In stock
CDX-A0326-G02525 gCHF 54.00
CDX-A0326-G100100 gCHF 150.00
| Product Details | |
|---|---|
| Synonyms | H-D-Asp-OH; D-Aspartate; D-Asp; (R)-(-)-Aminosuccinic acid; (R)-2-Aminosuccinic acid; D-Aminosuccinic acid |
| Product Type | Chemical |
| Properties | |
| Formula | C4H7NO4 |
| MW | 133.10 |
| CAS | 1783-96-6 |
| Purity Chemicals | ≥99% (Titration) |
| Appearance | White to off-white powder. |
| Solubility | Soluble in 1N ammonium hydroxide (100 mg/ml). Slightly soluble in water. |
| Identity | Determined by NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | CKLJMWTZIZZHCS-UWTATZPHSA-N |
| Smiles | O=C(O)[C@H](N)CC(O)=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Endogenous NMDA receptor agonist with similar activity to the L-isomer. Endogenous amino acid present in vertebrates and invertebrates, plays an important role in the neuroendocrine system, as well as in the development of the nervous system. Acts as a neurotransmitter/neuromodulator. Increases cAMP in neuronal cells and is transported from the synaptic clefts to presynaptic nerve cells through a specific transporter. In the endocrine system, D-Asp is involved in the regulation of hormone synthesis and release. Enhances gonadotropin-releasing hormone (GnRH) release and induces oxytocin and vasopressin mRNA synthesis in rats. In the pituitary gland, it stimulates the secretion of the hormones prolactin (PRL), luteinizing hormone (LH) and growth hormone (GH). Also involved in testosterone and progesterone release.
Product References
(1) H.J. Olverman, et al.; Neuroscience 26, 17 (1988) | (2) S. Ishio, et al; Neurosci. Lett. 249, 143 (1998) | (3) G. D'Aniello, et al.; Endocrinol. 141, 3862 (2000) | (4) A. D'Aniello; Brain Res. Rev. 53, 215 (2007) (Review) | (5) E. Topo, et al.; Reprod. Biol. Endocrinol. 7, 120 (2009) | (6) E. Topo, et al.; Amino Acids 38, 1561 (2010) | (7) S. D'Aniello, et al.; FASEB J. 25, 1014 (2011)
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