D-Aspartic acid

CHF 51.00
In stock
CDX-A0326-G02525 gCHF 51.00
CDX-A0326-G100100 gCHF 140.00
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Product Details
Synonyms H-D-Asp-OH; D-Aspartate; D-Asp; (R)-(-)-Aminosuccinic acid; (R)-2-Aminosuccinic acid; D-Aminosuccinic acid
Product Type Chemical
Properties
Formula C4H7NO4
MW 133.10
CAS 1783-96-6
Purity Chemicals ≥99% (Titration)
Appearance White to off-white powder.
Solubility Soluble in 1N ammonium hydroxide (100 mg/ml). Slightly soluble in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key CKLJMWTZIZZHCS-UWTATZPHSA-N
Smiles O=C(O)[C@H](N)CC(O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at RT.
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Product Specification Sheet
Datasheet Download PDF

Endogenous NMDA receptor agonist with similar activity to the L-isomer. Endogenous amino acid present in vertebrates and invertebrates, plays an important role in the neuroendocrine system, as well as in the development of the nervous system. Acts as a neurotransmitter/neuromodulator. Increases cAMP in neuronal cells and is transported from the synaptic clefts to presynaptic nerve cells through a specific transporter. In the endocrine system, D-Asp is involved in the regulation of hormone synthesis and release. Enhances gonadotropin-releasing hormone (GnRH) release and induces oxytocin and vasopressin mRNA synthesis in rats. In the pituitary gland, it stimulates the secretion of the hormones prolactin (PRL), luteinizing hormone (LH) and growth hormone (GH). Also involved in testosterone and progesterone release.

Product References

(1) H.J. Olverman, et al.; Neuroscience 26, 17 (1988) | (2) S. Ishio, et al; Neurosci. Lett. 249, 143 (1998) | (3) G. D'Aniello, et al.; Endocrinol. 141, 3862 (2000) | (4) A. D'Aniello; Brain Res. Rev. 53, 215 (2007) (Review) | (5) E. Topo, et al.; Reprod. Biol. Endocrinol. 7, 120 (2009) | (6) E. Topo, et al.; Amino Acids 38, 1561 (2010) | (7) S. D'Aniello, et al.; FASEB J. 25, 1014 (2011)

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