D-(-)-Ribose

CHF 51.00
In stock
CDX-R0065-G02525 gCHF 51.00
CDX-R0065-G100100 gCHF 83.00
CDX-R0065-G250250 gCHF 179.00
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Product Details
Synonyms (2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal; Ribose
Product Type Chemical
Properties
Formula C5H10O5
MW 150.13
CAS 50-69-1
Purity Chemicals ≥98% (HPLC)
Appearance White to off-white powder.
Solubility Soluble in water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key PYMYPHUHKUWMLA-LMVFSUKVSA-N
Smiles O=C([H])[C@@H]([C@@H]([C@@H](CO)O)O)O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +20°C
Long Term Storage +4°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Aldopentose monosaccharide that is phosphorylated into D-ribose 5-phosphate by ribokinase. D-ribose-5-phosphate supports the biosynthesis of the amino acids tryptophan and histidine, and is a component in the pentose phosphate pathway. D-ribose is present in all living cells and their microenvironments and is a key component of numerous biomolecules involved in many important metabolic pathways. It also participates in the glycation of proteins producing advanced glycation end products (AGEs) that lead to cell dysfunction and death. Ribosylation, has been shown to cause protein aggregation in vitro and in vivo. Has demonstrated significant enhancing abilities in replenishing deficient cellular energy levels following myocardial ischemia, improving depressed function in numerous animal investigations and showing cellular protection during oxidative stress. D-Ribose is used as a supplement in cell culture and as a building block for synthesis.

Product References

(1) L.M. Shecterle, et al.; Recent Pat. Cardiovasc. Drug Discov. 5, 138 (2010) | (2) P. Addis, et al.; J. Diet. Suppl. 9, 178 (2012) | (3) Y. Wei, et al.; Biochim. Biophys. Acta 1820, 488 (2012) | (4) N. Minakawa & A. Matsuda; Curr. Protoc. Nucleic Acid Chem. 59, 14 (2014)

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