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Chemodex
Artemisinin
61
CHF
CHF 61.00
In stock
CDX-A0335-M100100 mgCHF 61.00
| Product Details | |
|---|---|
| Synonyms | Arteannuin; Qinghaosu; NSC 369397 |
| Product Type | Chemical |
| Properties | |
| Formula |
C15H22O5 |
| MW | 282.33 |
| CAS | 63968-64-9 |
| RTECS | KD4170000 |
| Source/Host Chemicals | Isolated from plant source. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | White powder. |
| Solubility | Soluble in DMSO (10mg/ml), ethanol (15mg/ml), methanol or choroform (25mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | BLUAFEHZUWYNDE-NNWCWBAJSA-N |
| Smiles | [H][C@](OC([C@@H]([C@@]1(CC[C@H]([C@@]2(CC3)[H])C)[H])C)=O)([C@]12OO4)O[C@]43C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Artemisinin is an antimalarial agent with anticancer activity. It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. Artemisinin induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells.
Product References
(1) A. Zyad, et al.; Phytother. Res. 32, 216 (2018) | (2) E. Konstat-Korzenny, et al.; Med. Sci. 6, E19 (2018) | (3) Y. Zhang, et al.; Nat. Prod. Bioprospect. 8, 303 (2018) | (4) A. Kumari, et al.; Eur. J. Med. Chem. 163, 804 (2019)