Chemodex

Arbutin

CHF 81.00

In stock

CDX-A0402-G01010 gCHF 81.00

CDX-A0402-G02525 gCHF 162.00

CDX-A0402-G05050 gCHF 285.00

More Information
Product Details
Synonyms	β-Arbutin; NSC 4036; 4-Hydroxyphenyl-β-D-glucopyranoside; p-Arbutin; Hydroquinone β-D-glucopyranoside
Product Type	Chemical
Properties
Formula	C₁₂H₁₆O₇
MW	272.25
CAS	497-76-7
RTECS	CE8863000
Source/Host Chemicals	Plant
Purity Chemicals	≥98% (HPLC)
Appearance	Light yellow powder.
Solubility	Soluble in DMSO (10mg/ml), ethanol (1mg/ml) or water (25mg/ml).
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	BJRNKVDFDLYUGJ-RMPHRYRLSA-N
Smiles	O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](OC2=CC=C(O)C=C2)[C@@H]1O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+20°C
Long Term Storage	+20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at RT.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Arbutin is a glycosylated hydroquinone used in traditional Chinese medicine (TCM) that has been found in Arctostaphylos plants and has diverse biological activities, including tyrosinase inhibitory, antioxidant, anti-tumor and anti-inflammatory properties. Arbutin is a competitive inhibitor of tyrosinase in melanocytes (suppressing production of melanin) and therefore used as a skin-lightening agent and in the treatment of hyperpigmentation disorders.

Product References

(1) K. Maeda & M. Fukuda; JPET 276, 765 (1996) | (2) J. Takebayashi, et al.; Free Radic. Res. 44, 473 (2010) | (3) D.-H. Seo, et al.; Appl. Microbiol. Biotechnol. 95, 1417 (2012) | (4) A. Garcia-Jimenez, et al.; PLoS One 12, e0177330 (2017) | (5) J. Ye, et al.; Pulm. Pharmacol. Ther. 54, 53 (2019)

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