Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Chemodex
Asiaticoside
150
CHF
CHF 150.00
In stock
CDX-A0575-M02525 mgCHF 150.00
CDX-A0575-M100100 mgCHF 447.00
| Product Details | |
|---|---|
| Synonyms | Blastostimulina; Centelase; Emdecassol; Madecassol; Marticassol; FK1080; BRN 0078195; NSC 166062 |
| Product Type | Chemical |
| Properties | |
| Formula |
C48H78O19 |
| MW | 959.133 |
| CAS | 16830-15-2 |
| RTECS | YU9625000 |
| Source/Host Chemicals | Plant |
| Purity Chemicals | ≥95% (NMR) |
| Appearance | White creamy powder. |
| Solubility | Soluble in DMSO or ethanol. Slightly soluble in methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | WYQVAPGDARQUBT-NXDSUYQXSA-N |
| Smiles | O[C@H]1[C@H](O)[C@@](C)(CO)C(CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(O[C@@H]6O[C@H](CO[C@@H]7O[C@H](CO)[C@@H](OC8O[C@H](C)[C@H](O)[C@@H](O)[C@@H]8O)[C@H](O)[C@H]7O)[C@@H](O)[C@H](O)[C@H]6O)=O)C4[C@@H](C)[C@H](C)CC5)[C@]3(C)C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Asiaticoside is the main saponin constituent of C. asiatica, a plant long used in the Ayurvedic system of medicine to treat dermatitis, diabetes, cough, cataract, hypertension, as well as for wound healing and improving memory. It is a human collagen I synthesis inducer with anti-wrinkle activity. It shows wound healing activity, enhancing normal human skin cell migration, attachment and growth. Asiaticoside is an anti-inflammatory compound that inibits MAPKs, NF-κ, COX-2 and iNOS expression, and production of TNF-α and IL-6. Also shown to induce apoptosis and autophagy in cancer cells. Described to have also antibacterial, antioxidant, anxiolytic, antidepressant-like, hepatoprotective, neuroprotective and antileishmanial activity.
Product References
(1) A. Shukla, et al.; J. Ethnopharmacol. 65, 1 (1999) | (2) J.H. Sampson, et al.; Phytomedicine 8, 230 (2001) | (3) J.S. Guo, et al.; Planta Med. 70, 1150 (2004) | (4) J.S. Ryu, et al.; Skin Res. Technol. 11, 157 (2005) | (5) S.W. Chen, et al.; Pharmacol. Biochem. Behav. 85, 339 (2006) | (6) X. Liang, et al.; Pharmacol. Biochem. Behav. 89, 444 (2008) | (7) C.L. Xu, et al.; Pharmacol. Biochem. Behav. 100, 413 (2012) | (8) S.K. Bhaumik, et al.; J. Antimicrob. Chemother. 67, 910 (2012) | (9) J.H. Lee, et al.; Phytomedicine 19, 1223 (2012) | (10) J. Wan, et al.; Phytother. Res. 27, 1136 (2013) | (11) F.Y. Qi, et al.; Neural. Regen. Res. 9, 1275 (2014) | (12) Y. Luo, et al.; Mol. Med. Rep. 12, 8294 (2015) | (13) Q. Hou, et al.; Exp. Ther. Med. 12, 1269 (2016) | (14) X. Wang, et al.; Mol. Med. Rep. 17, 2893 (2018) | (15) L. Jing, et al.; Cytotechnology 70, 855 (2018) | (16) L. Yingchun, et al.; Med. Sci. Monit. 25, 1355 (2019)