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Chemodex
Adenosine
115
CHF
CHF 115.00
In stock
CDX-A0657-G05050 gCHF 115.00
CDX-A0657-G100100 gCHF 189.00
| Product Details | |
|---|---|
| Synonyms | 9-β-D-Ribofuranosyladenine; Adenine riboside; Adenine-9-β-D-ribofuranoside; NSC 7652 |
| Product Type | Chemical |
| Properties | |
| Formula |
C10H13N5O4 |
| MW | 267.24 |
| CAS | 58-61-7 |
| RTECS | AU7175000 |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | White to off white powder. |
| Solubility | Soluble in water (7mg/ml) or DMSO (75 mM). Insoluble in ethanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | OIRDTQYFTABQOQ-KQYNXXCUSA-N |
| Smiles | O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]1CO |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +4°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
Adenosine is a purine nucleoside composed of adenine and ribose linked by a glycosidic linkage. Adenosine is a key endogenous neurotransmitter that regulates tissue function in an anti- and pro-inflammatory manner by activating four G-protein-coupled adenosine receptors: A1, A2A, A2B and A3, which serve diverse roles related to smooth muscle tone, central nervous system regulation and cardiac function. Cells of the immune system express these receptors and are responsive to the modulatory effects of adenosine in an inflammatory environment. Adenosine is a precursor for adenosine 5’-monophosphate, adenosine 5’-diphosphate, adenosine 5’-triphosphate and cyclic AMP.
Product References
(1) G. Hasko & B.N. Cronstein; Trends Immunol. 25, 33 (2004) | (2) K.A. Jacobson & Z.G. Gao; Nat. Rev. Drug Discov. 5, 247 (2006) (Review) | (3) G. Hasko, et al.; Nat. Rev. Drug Discov. 7, 759 (2008) (Review) | (4) S. Nakav, et al.; PLoS One 3, e2107 (2008)