Chemodex

Alizarin Red S

Name: Alizarin Red S
Brand: Chemodex
SKU: CDX-A0670
Price: 77.00 CHF
Availability: InStock

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CDX-A0670-G05050 gCHF 77.00

Specifications / Handling

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Product Details
Synonyms	3,4-Dihydroxy-9,10-dioxo-2-anthracenesulfonic acid sodium salt; C.I. 58005; Alizarin Carmine; Alizarin Red; Alizarinsulfonate; Ahcoquinone Red S; Alizarin sulfonate sodium; Chrome Red Alizarine
Product Type	Chemical
Properties
Formula	C₁₄H₇NaO₇S
MW	342.26
CAS	130-22-3
RTECS	CB1095300
Source/Host Chemicals	Synthetic
Purity Chemicals	≥70% (Dye content)
Appearance	Brownish yellow powder.
Solubility	Soluble in DMSO (10mg/ml) or water (1mg/ml).
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	HFVAFDPGUJEFBQ-UHFFFAOYSA-M
Smiles	[Na+].Oc1c(O)c(cc2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+20°C
Long Term Storage	+20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at RT.
Documents
Product Specification Sheet
Datasheet	Download PDF

Scientific Background Information

Product Description

Alizarin Red S is a well-established anionic anthraquinone dye widely used as a pH indicator or for the detection and quantification of calcium and other divalent metal ions. It forms a bright red to orange-red complex with calcium salts, making it a standard reagent for histological staining and cell culture assays involving mineralization. In biomedical research, Alizarin Red S is most commonly used to assess osteogenic differentiation by staining calcium deposits in cultured cells and tissue sections. The dye is also employed in analytical chemistry and materials science for metal ion binding studies due to its strong chelation properties. Its strong color response and reliable metal-binding properties make it an excellent choice for osteogenesis studies, histological staining, and spectrophotometric analysis in both research and quality control laboratories. It acts as a colorometric pH indicator. 1st transition range: pH 4.3 - pH 6.3 Lightly yellow - pink/red. 2nd transition range: pH 9.4 - pH 12.0 Brown orange - violet.

Product-specific References

[1] K.F. Adkins; Stain Technol. 40, 69 (1965) | [2] H. Puchtler, et al.; J. Histochem. Cytochem. 17, 110 (1969) | [3] P. Virtanen & K. Isotupa; Acta Anat. 108, 202 (1980) | [4] F. Eggelmeijer, et al.; Clin. Exp. Rheumatol. 9, 11 (1991) | [5] K. Basavaiah, et al.; Talanta 50, 887 (1999) | [6] G. Springsteen & B. Wang; Chem. Commun. 7, 1608 (2001) | [7] I. Sahin & N. Nakiboglu; Anal. Chim. Acta 572, 253 (2006) | [8] S.A. Sangsefedi, et al.; J. Fluoresc. 28, 815 (2018) | [9] W. Ma, et al.; Polymers 11, 165 (2019) | [10] A. Bernar, et al.; Int. J. Mol. Sci. 24, 723 (2022) | [11] C.A.N. Catalan, et al.; Molecules 30, 3286 (2025)

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