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Chemodex
4-Aminobenzamidine dihydrochloride
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CHF
CHF 168.00
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CDX-A0920-G0055 gCHF 168.00
CDX-A0920-G02525 gCHF 638.00
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Product Details | |
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Synonyms | 4-ABA; p-Aminobenzamidine dihydrochloride |
Product Type | Chemical |
Properties | |
Formula | C7H9N3 . 2HCl |
MW | 208.09 |
CAS | 2498-50-2 |
RTECS | CV6126500 |
Source/Host Chemicals | Synthetic |
Purity Chemicals | ≥99% (TLC) |
Appearance | Off-white powder. |
Solubility | Soluble in water. |
Identity | Determined by 1H-NMR. |
Declaration | Manufactured by Chemodex. |
Other Product Data |
Click here for Original Manufacturer Product Datasheet |
InChi Key | GHEHNICLPWTXJC-UHFFFAOYSA-N |
Smiles | C(=N)(N)C1=CC=C(N)C=C1.Cl |
Shipping and Handling | |
Shipping | AMBIENT |
Short Term Storage | +20°C |
Long Term Storage | +4°C |
Handling Advice | Protect from light and moisture. |
Use/Stability | Stable for at least 2 years after receipt when stored at +4°C. |
Documents | |
Product Specification Sheet | |
Datasheet |
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Description
4-Aminobenzamidine dihydrochloride can be used as a building block in organic synthesis as well as for investigating enzyme kinetics. It is used as a ligand in affinity chromatography for purification and immobilization of enzymes. This benzamidine derivative is a selective and potent serine protease inhibitors. It functions as a reversible inhibitor of enzymes and ion transporters by binding to their active sites. By doing so, it hinders their interaction with substrates, consequently impeding their activity.
Product References
(1) S.A.Beyler & L.J. Zaneveld; J. Reprod. Fertil. 66, 425 (1982) | (2) D.M. Monroe, et al.; Anal. Biochem. 172, 427 (1988) | (3) S. Khamlichi, et al.; J. Chromatogr. 510, 123 (1990) | (4) S. Krishnaswamy, et al.; J. Biol. Chem. 267, 26110 (1992) | (5) F. Dudouit, et al.; J. Heterocyc. Chem. 38, 755 (2001) | (6) M.F. Gouzy, et al.; Biomaterials 25, 3493 (2004) | (7) S.G. De-Simone, et al.; J. Chromatogr. B. Anal. Technol. Biomed. Life Sci. 822, 1 (2005) | (8) E.I. Klimova, et al.; Molecules 19, 41 (2013)