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Chemodex
7-Acetoxycoumarin
As low as
380
CHF
CHF 380.00
In stock
Only %1 left
CDX-A0984-M05050 mgCHF 380.00
CDX-A0984-M100100 mgCHF 612.00
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Specifications / Handling
| Product Details | |
|---|---|
| Synonyms | 7AC; 7-Hydroxycoumarin acetate; Acetylumbelliferone; 2-Oxo-2H-chromen-7-yl acetate; Umbelliferone acetate |
| Product Type | Chemical |
| Properties | |
| Formula | C11H8O4 |
| MW | 204.18 |
| CAS | 10387-49-2 |
| Source/Host Chemicals | Synthetic |
| Purity Chemicals | ≥97% (HPLC) |
| Appearance | Off-white to beige powder. |
| Solubility | Soluble in chloroform or DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| InChi Key | MGZOXZPZHVOXQB-UHFFFAOYSA-N |
| Smiles | O=C1OC2=C(C=CC(OC(C)=O)=C2)C=C1 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light and moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Scientific Background Information
Product Description
7-Acetoxycoumarin is a coumarin derivative widely used as a synthetic intermediate in organic and medicinal chemistry research. The acetoxy functional group provides a convenient site for chemical modification, making this compound a valuable building block for the synthesis of fluorescent probes, biologically active molecules, and specialty materials. 7-Acetoxycoumarin is commonly employed in studies involving coumarin-based compounds and their applications in chemical and pharmaceutical research. 7-Acetoxycoumarin also has been shown to have anti-inflammatory properties in cell-based studies. It significantly inhibits inflammatory responses in LPS-stimulated RAW 264.7 macrophage cells.
Product-specific References
(1) G.G. Guilbault, et al.; Anal. Lett. 1, 551 (1968) | (2) E. Leroy, et al.; Bioorg. Med. Chem. Lett. 13, 2105 (2003) | (3) F. Huo, et al.; Analyst 138, 813 (2013) | (4) S. Yang, et al.; Tetrahedr. 70, 8914 (2014) | (5) T. Park, et al.; Molecules 25, 3124 (2020)