Biotin-X

Specifications / Handling

More Information
Product Details
Synonyms	N-(+)-Biotinyl-6-aminohexanoic acid; Biotin caproic acid; (+)-Biotin-epsilon-aminocaproic acid; 6-((Biotinoyl)amino)hexanoic acid; N-(+)-Biotinyl-6-aminocaproic acid
Product Type	Chemical
Properties
Formula	C₁₆H₂₇N₃O₄S
MW	357.47
CAS	72040-64-3
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥98% (HPLC)
Appearance	White to off-white powder.
Solubility	Soluble in DMSO or DMF (slightly).
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	CMUGHZFPFWNUQT-HUBLWGQQSA-N
Smiles	O=C(NCCCCCC(O)=O)CCCC[C@@H]1SC[C@@]2([H])[C@]1([H])NC(N2)=O
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Biotin-X is an amino-reactive biotinylation reagent with a long spacer arm. The 6-aminocaproic acid spacer arm provides distance between the biotin and the target ligand which helps alleviate steric hindrance. Biotin-X can be used to biotinylate antibodies, proteins, peptides, or amino acids by reacting with primary amines as found in the N-terminus and Lysine side chains. Biotin-X may also be used in the biosynthesis of biotinylated oligosaccharides. Optimal reaction conditions are at a pH of 7-9. Avoid amine-containing buffers, which may compete in the acylation reaction.

Product References

(1) G.T. Hermanson; Bioconjugate Techn. 2nd p506-545 (2008)

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